Thanks to some tips from online forums I was able to get to the bottom of this. I'd already tried:
- Reinstalling Office
- Registry cleaner (ccleaner)
- Log on as a different user
- Chkdsk
- Performance monitor
- File type associations
- Disable DDE
So what was happening?
This post pointed me to the answer http://howtotroubleshoot.blogspot.com/2008/05/double-clicked-documents-slow-to-open.html
On this occasion running netstat -ano in the command shell showed me that the desktop was connected to only the server and the router until I tried to open a Word document when suddenly it sent a SYN packet to another local IP - this user's old computer.
There were no mapped drives to this computer and searching the registry for the IP address gave no results. However when I searched the registry for the old computer's name then it came up under several keys relating to Firefox.
I uninstalled firefox but the problem didn't go away. I did another search of the registry and this entry still came up under a firefox key so I simply deleted it. Hey presto! Problem solved.
Don't ask me why but this is how I solved it.
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